MK-677 (Ibutamoren) is a growth hormone secretagogue, which mimics the growth hormone. It also increases insulin-like growth factor 1 (IGF-1). Researchers have found MK-677 to help build muscle, reduce muscle wasting, increase bone density, and reverse aging.
Growth hormone pulse intensity can be increased through 4 possible mechanisms:
How it works: MK-677 increases growth hormone levels and binding to one of the ghrelin receptors (GHSR) in the brain. Activated GHSR stimulates growth hormone release. GHSR is found in brain regions that control appetite, pleasure